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徐慧萍


hsu

姓名:徐慧萍醫師

主要學歷

畢業學校

科系所

學位

成功大學

臨床醫學研究所

博士

成功大學

醫學系

學士

現職

服務機關

服務部門

職稱

成大醫院

外科部

教授

成大醫院

外科部

主治醫師

經歷

服務機關

服務部門

職稱

成大醫院斗六分院

外科部

主治醫師

專長

臨床

一般外科、乳房外科、腫瘤外科

研究

腫瘤學

學術成大

學術論文

  1. Tsung-Ming Chang†, Wei-Yu Fang†, Hui-Ping Hsu†, Pei-Yi Chu, Shih-Sheng Jiang, Kuo-Wei Huang, Wen-Chun Hung, Hui-You Lin, Hui-Jen Tsai*. PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-β/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquitination. Cancer Biol Ther 2025 Dec; 26(1): 2478670. (SCI, co-first author)
  2. Pei-An Fu, Ya-Chun Hsu, Hui-Ping Hsu, Tzu-Chien Lin, Wei-Pang Chung*. Premenopausal patients with clinically aggressive metastatic breast cancer successfully treated with a first-line palbociclib-containing regimen: two cases and literature review. Cancer Rep (Hoboken) 2025 Dec; 8(12): e70417. (ESCI, case report)
  3. I-Sung Chen†, Chi-Che Hsieh†, Chun-Chun Li, You-Lin Wei, Chao-Chun Cheng, Sheng-Wei Feng, Hsin-Lun Lee, Nai-Jung Chiang*, Che-Hung Shen*, Hui-Ping Hsu*. ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer. Oncogenesis 2025 Nov 21; 14(1): 45.(SCI, co-corresponding author).
  4. Cheng-Han Lee, I-Sung Chen, Ying-Jui Chao, Hui-Ping Hsu*. High plasma histidine concentration predicts a favorable prognosis in patients with ampullary cancer. Am J Cancer Res 2025 Oct; 15(10): 4452-4469. (SCI, corresponding author).
  5. Tzu-Hui Wei, Chi-Che Hsieh, Zhu-Jun Loh, Wei-Pang Chung, Kuo-Ting Lee, Yi-Ling Chen*, Hui-Ping Hsu*, Che-Hung Shen*. Suppression of STK11 induces expansion of polymorphonuclear myeloid-derived suppressive cells and activation of immune signaling in breast cancer. Cancer Immunol Immunother 2025 Oct 6;74(11):328. (SCI, co-corresponding author)
  6. Yu-Ling Hsu, Chun-Hui Lee, Wei-Pang Chung, Wen-Huang Lee, Kuo-Ting Lee, Jui-Hung Tsai, Hui-Ping Hsu, Shuen-Ru Yang, Zhu-Jun Loh, Pei-Fang Su, Chao-Ming Hung, Wei-Chuan Tsai, Yen-Wen Liu, Ping-Yen Liu. Primary cardioprotective effect of sacubitril/valsartan in breast cancer patients receiving adjuvant therapy. Eur J Heart Fail 2025 Nov;27(11):2141-2151.
  7. You-Yu Liu, Wei-Lun Huang, Sin-Tian Wang, Hui-Ping Hsu, Tzu-Ching Kao, Wei-Pang Chung*, Kung-Chia Young*. CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells. Cancer Metab. 2025 Feb 7;13(1):6.
  8. Han-Kun Chen, Yi-Ling Chen, Wei-Pang Chung, Zhu-Jun Loh, Kuo-Ting Lee, Hui-Ping Hsu*. Circulating CD3+CD8+ T lymphocytes as indicators of disease status in patients with early breast cancer. Cancer Med 2025 Jan; 14(1): e70547. (SCI, corresponding author)
  9. Kuo-Ting Lee, Dao-Peng Chen, Zhu-Jun Loh, Wei-Pang Chung, Chih-Yang Wang, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Hui-Ping Hsu*. Benign polymorphisms in the BRCA genes with linkage disequilibrium is associated with cancer characteristics. Cancer Sci 2024 Dec; 115(12): 3973-3985. (SCI, corresponding author)
  10. Han-Kun Chen, Yi-Ling Chen, Chih-Yang Wang, Wei-Pang Chung, Jung-Hua Fang, Ming-Derg Lai, Hui-Ping Hsu*. ABCB1 regulates immune genes in breast cancer. Breast Cancer – Targets Ther (Dove Med Press) 2023 Nov 13; 15: 801-811. (SCI, corresponding author)
  11. Chih-Yang Wang, Do Thi Minh Xuan, Pei-Hsuan Ye, Chung-Yen Li, Gangga Anuraga, Hoang Dang Khoa Ta, Ming-Derg Lai, Hui-Ping Hsu*. Synergistic suppressive effects on triple-negative breast cancer by the combination of JTC-801 and sodium oxamate. Am J Cancer Res 2023 Oct 15; 13(10): 4661-4677. (SCI, corresponding author)
  12. Chung-Yen Li, Gangga Anuraga, Chih-Peng Chang, Tzu-Yang Weng, Hui-Ping Hsu, Hoang Dang Khoa Ta, Pei-Fang Su, Pin-Hsuan Chiu, Shiang-Jie Yang, Feng-Wei Chen, Pei-Hsuan Ye, Chih-Yang Wang, Ming-Derg Lai. Repurposing nitric oxide donating drugs in cancer therapy through immune modulation. J Exp Clin Cancer Res 2023 Jan 14; 42(1): 22. (SCI)
  13. Do Thi Minh Xuan, Chung-Che Wu, Wei-Jan Wang, Hui-Ping Hsu, Hoang Dang Khoa Ta, Gangga Anuraga, Chung-Chieh Chiao, Chih-Yang Wang. Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. Int J Med Sci 2023 Jan 1; 20(1): 35-49. (SCI)
  14. Hui-Ping Hsu, Pei-Yi Chu, Tsung-Ming Chang, Kuo-Wei Huang, Wen-Chun Hung, Shih Sheng Jiang, Hui-You Lin, Hui-Jen Tsai*. Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor-positive breast cancer via regulation of the mTOR pathway. Cancer Med. 2023 Jan; 12(2): 1588-1601. (SCI, co-first authors)
  15. Wei-Pang Chung, Wei-Lun Huang, Chun-Hui Lee, Hui-Ping Hsu, Wan-Ling Huang, You-Yu Liu, Wu-Chou Su*. PI3K inhibitors in trastuzumab-resistant HER2-positive breast cancer cells with PI3K pathway alterations. Am J Cancer Res 2022 Jul 15; 12(7): 3067-3082. (SCI)
  16. Yi-Ling Chen, Kuo-Ting Lee, Chih-Yang Wang, Che-Hung Shen, Sheau-Chiann Chen, Wei-Pang Chung, Ya-Ting Hsu, Yao-Lung Kuo, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Meng-Ru Shen, Hui-Ping Hsu*. Low expression of cytosolic NOTCH1 predicts poor prognosis of breast cancer patients. Am J Cancer Res 2022 May 15; 12(5): 2084-2101. (SCI, corresponding author)
  17. Pang-Shuo Perng, Hui-Ping Hsu, Po-Hsuan Lee, Chi-Chen Huang, Chien-Chung Lin, Jung-Shun Lee. Correlation of EGFR mutation subtypes and survival in surgically treated non-small cell lung cancer brain metastasis. Asian J Surg. 2023 Jan;46(1):269-276. (SCI)
  18. Yi-Ling Chen, Chih-Yang Wang, Jung-Hua Fang, Hui-Ping Hsu*. Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness. Am J Cancer Res. 2021 Sep 15; 11(9): 4277-4293. (SCI, corresponding author)
  19. Peng-Chan Lin, Yu-Min Yeh, Hui-Ping Hsu, Ren-Hao Chan, Bo-Wen Lin, Po-Chuan Chen, Chien-Chang Pan, Keng-Fu Hsu, Jenn-Ren Hsiao, Yan-Shen Shan, Meng-Ru Shen*. Comprehensively exploring the mutational landscape and patterns of genomic evolution in hypermutated cancers. Cancers (Basel) 2021 Aug 26; 13(17): 4317. (SCI)
  20. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells. J Microbiol Immunol Infect 2021 Oct; 54(5): 845-857. (SCI, co-corresponding author)
  21. Zhu-Jun Loh, Kuo-Ting Lee, Ya-Ping Chen, Yao-Lung Kuo, Wei-Pang Chung, Ya-Ting Hsu, Chien-Chang Huang, Hui-Ping Hsu*. False-Negative frozen section of sentinel nodes in early breast cancer (cT1-2N0) patients. World J Surg Oncol 2021; 19(1): 183. (SCI, corresponding author)
  22. Li-Chin Cheng, Tzu-Jen Kao, Nam Nhut Phan, Chung-Chieh Chiao, Meng-Chi Yen, Chien-Fu Chen, Jui-Hsiang Hung, Jia-Zhen Jiang, Zhengda Sun, Chih-Yang Wang*, Hui-Ping Hsu*. Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease. Medicine 2021; 100(7): e24321 (SCI, co-corresponding author)
  23. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Hsin-Liang Liu, Chih-Yang Wang*, Hui-Ping Hsu*. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis. Int J Med Sci 2021; 18(5): 1143-1152. (SCI, co-corresponding author)
  24. Wei-Pang Chung, Kuo-Ting Lee, Ya-Ping Chen, Ya-Ting Hsu, Zhu-Jun Loh, Chien-Chang Huang, Hui-Ping Hsu*. The prognosis of early-stage breast cancer in extremely young female patients in a single institute. Medicine 2021; 100(1): e24076. (SCI, corresponding author)
  25. Pin-Shern Chen†, Hui-Ping Hsu†, Nam Nhut Phan, Meng-Chi Yen, Feng-Wei Chen, Yu-Wei Liu, Fang-Ping Lin, Sheng-Yao Feng, Tsung-Lin Cheng, Pei-Hsiang Yeh, Hany A Omar, Zhengda Sun, Jia-Zhen Jiang, Yi-Shin Chan, Ming-Derg Lai, Chih-Yang Wang*, Jui-Hsiang Hung*. CCDC167 as a potential therapeutic target and regulator of cell cycle-related networks in breast cancer. Aging-US 2021; 13(3): 4157-4181. (SCI, co-first authors)
  26. Chih-Yang Wang, Ying-Jui Chao, Yi-Ling Chen, Tzu-Wen Wang, Nam Nhut Phan, Hui-Ping Hsu*, Yan-Shen Shan, Ming-Derg Lai. Upregulation of peroxisome proliferator-activated receptor-α and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer. Int J Med Sci 2021; 18(1): 256-269. (SCI, corresponding author)
  27. Li-Chin Cheng, Ying-Jui Chao, Michael J. Overman, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yan-Shen Shan*, Ming-Derg Lai. Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence. Sci Rep 2020; 10: 13255. (SCI, co-corresponding authors)
  28. Li-Chin Cheng, Ying-Jui Chao, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yih-Jyh Lin, Yan-Shen Shan*, Ming-Derg Lai. Cancer-derived transforming growth factor-b modulates tumor-associated macrophages in ampullary cancer. OncoTargets Ther 2020; 13: 7503-7516. (SCI, co-corresponding authors)
  29. Yi-Yi Lin, Chih-Yang Wang, Nam Nhut Phan, Chung-Chieh Chiao, Chung-Yen Li, Zhengda Sun, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Hui-Ping Hsu*, Ming-Derg Lai*. PODXL2 maintains cellular stemness and promotes breast cancer development through the Rac1/Akt pathway. Int J Med Sci 2020; 17(11): 1639-1651. (SCI, co-corresponding authors)
  30. Hsin-Liang Liu, I-Jeng Yeh, Nam Nhut Phan, Yen-Hung Wu, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Jia-Zhen Jiang, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models. Infect Genet Evol 2020; 104438. (SCI, co-corresponding authors)
  31. Nam Nhut Phan, Shirui Liu, Chih-Yang Wang, Hui-Ping Hsu, Ming-Derg Lai, Chung-Yen Li, Chien-Fu Chen, Chung-Chieh Chiao, Meng-Chi Yen, Zhengda Sun, Jia-Zhen Jiang*. Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database. Int J Clin Exp Pathol 2020; 13(5): 1220-1242. (SCI, co-first authors)
  32. Chih-Yang Wang, Chung-Chieh Chiao, Nam Nhut Phan, Chung-Yen Li, Zheng-Da Sun, Jia-Zhen Jiang, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Hui-Ping Hsu*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer. Am J Cancer Res 2020; 10(1): 95-113. (SCI, co-corresponding authors)
  33. Hui-Ping Hsu, Chih-Yang Wang, Pei-Yin Hsieh, Jung-Hua Fang, Yi-Ling Chen*. Knockdown of serine/threonine-protein kinase 24 promotes tumorigenesis and myeloid-derived suppressor cell expansion in an orthotopic immunocompetent gastric cancer animal model. J Cancer 2020; 11(1): 213-228. (SCI, first author)
  34. Chih-Yang Wang, Yung-Chieh Chang, Yao-Lung Kuo, Kuo-Ting Lee, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Nam Nhut Phan, Meng-Ru Shen, Hui-Ping Hsu*. Mutation of the PTCH1 gene predicts recurrence of breast cancer. Sci Rep 2019; 9: 16359.1-1639.14. (SCI, corresponding author)
  35. Chia-Yi Su, Ruei-Liang Yan, Wen-Hsin Hsu, Ching-Tung Chu, Hsuan-Chia Chang, Chien-Chen Lai, Hui-Ping Hsu, Hong-Chen Chen*. Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Sci Rep 2019; 9(1): 13703.e1-13703.e11. (SCI)
  36. Wei-Pang Chung, Ya-Tin Hsu, Ya-Ping Chen, Hui-Ping Hsu*. Treatment of a patient with breast cancer and glucose 6-phosphate dehydrogenase deficiency: a case report. Medicine 2019; 98(13): e14987.1-e14987.3. (SCI, corresponding author)
  37. Tsung-Han Yang, Jen-Lung Chen, Yih-Jyh Lin, Ying-Jui Chao, Yan-Shen Shan, Hui-Ping Hsu, Zhe-Min Su, Chung-Ching Chou, Yi-Ting Yen*. Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes. Surg Endosc 2018; 32(10): 4314-4320. (SCI)
  38. Tzu-Yang Weng, Hsuan Franziska Wu, Chung-Yen Li, Yu-Hsuan Hung, Yu-Wei Chang, Yi-Ling Chen, Hui-Ping Hsu, Yu-Hung Chen, Chih-Yang Wang, Jang-Yang Chang, Ming-Derg Lai*. Homoharringtonine induced immune alteration for an efficient anti-tumor response in mouse models of non-small cell lung adenocarcinoma expressing Kras Mutation. Sci Rep 2018; 8(1): 8216. (SCI)
  39. Tzu-Yang Weng, Chia-Jung Li, Chung-Yen Li, Yu-Hsuan Hung, Meng-Chi Yen, Yu-Wei Chang, Yu-Hung Chen, Yi-Ling Chen, Hui-Ping Hsu, Jang-Yang Chang, Ming-Derg Lai*. Skin delivery of Clec4a small hairpin RNA elicited an effective antitumor response by enhancing CD8+ immunity in vivo. Mol Ther Nucleic Acids. 2017; 9: 419-427. (SCI)
  40. Chih-Yang Wang, Chung-Yen Li, Hui-Ping Hsu, Chien-Yu Cho, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Yu-Hsuan Hung, Kuo-Ting Lee, Jui-Hsiang Hung, Yi-Ling Chen, Ming-Derg Lai*. PSMB5 plays a dual role in cancer development and immunosuppression. Am J Cancer Res 2017; 7(11): 2103-2120. (SCI)
  41. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Yu-Hsuan Hung, Chih-Yang Wang, Meng-Chi Yen, Yi-Ling Chen*. Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer. Oncol Lett. 2017 Oct; 14(4): 4517-4526. doi: 10.3892/ol.2017.6736. (SCI, co-first authors)
  42. Hui-Ping Hsu, Ming-Derg Lai, Jenq-Chang Lee, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Jung-Hua Fang, Yi-Ling Chen*. Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling. Sci Rep. 2017 Jul 19; 7(1): 5823.e1-5823.e14. (SCI, first author)
  43. Zhu-Jun Loh, Kuo-Ting Lee, Wei-Pang Chung, Wen-Chung Chen, Hsueh-Li Kuo, Po-Jun Chen, Hsi-Huei Lu, Hui-Ping Hsu*. Invasive lobular carcinoma of the breast with synchronous colon metastasis. Formosan J Surg 2017 Apr; 50(2): 69-73. (Corresponding author)
  44. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai*. Silencing of argininosuccinate lyase inhibits colorectal cancer formation. Oncol Rep. 2017 Jan; 37(1): 163-170. (SCI)
  45. Wei-Ching Chen, Hui-Ping Hsu, Yu-Hsuan Hung, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, and Ming-Derg Lai*. Cancer stem cell marker CD90 inhibits the ovarian cancer formation via β3 integrin. Int J Oncol. 2016 Nov; 49(5): 1881-1889. (SCI)
  46. Ming-Jenn Chen, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Ming-Derg Lai. The membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia. Oncology Reports, 2016 Oct; 36(4): 1997-2008. (SCI, corresponding author)
  47. Chih-Ming Su, Ting-Yu Chang, Hui-Ping Hsu, Hui-Huang Lai, Jie-Ning Li, Yu-Jhen Lyu, Kuang-Tai Kuo, Ming-Te Huang, Jen-Liang Su, Pai-Sheng Chen*. A novel application of E1A in combination therapy with EGFR-TKI treatment in breast cancer. Oncotarget. 2016 Sep 27; 7(39): 63924-63936. (SCI)
  48. Chien-Yu Cho, Kuo-Ting Lee, Wei-Ching Chen, Chih-Yang Wang, Yung-Sheng Chang, Hau-Lun Huang, Hui-Ping Hsu, Meng-Chi Yen, Ming-Zong Lai, Ming-Derg Lai*. MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer. Oncotarget. 2016 Feb 20; 7(6). (SCI)
  49. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai*. Argininosuccinate lyase is a potential therapeutic target in breast cancer. Oncology Reports 2015 Dec; 34(6): 3131-3139. (SCI)
  50. Yan-Shen Shan, Yi-Ling Chen, Ming-Derg Lai, Hui-Ping Hsu*. Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer. Oncology Reports 2015 Dec; 33(1): 40-48. (SCI, corresponding author)
  51. Wei-Ching Chen, Yung-Sheng Chang, Hui-Ping Hsu, Meng-Chi Yen, Hau-Lun Huang, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, Po-Ting Lai, Ching-Shih Chen, Yih-Jyh Lin, Ming-Derg Lai*. Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer. Oncotarget 2015 Dec 15; 6(40): 42923-42937. (SCI)
  52. Cheng-Lin Wu, Ying-Jui Chao, Ta-Ming Yang, Yi-Ling Chen, Kung-Chao Chang, Hui-Ping Hsu*, Yan-Shen Shan, Ming-Derg Lai. Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44v is an indicator for recurrence in advanced cancer. BMC Cancer 2015 Nov 16; 15(1): 903.e1-903.e10. (SCI, corresponding author)
  53. Ting-Wei Lin, Hui-Ping Hsu*. Increased activity of factor VIII causing acute intestinal ischemic disorder with recurrent and multiple arterial thromboses. Formosan J Surg 2015 Oct; 48(5): 177-180. (Corresponding author)
  54. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Wei-Ching Chen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen*. Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines. Scientific Reports 2015 Apr 30; 5: 9783.e1-9783.e10. (SCI, co-first authors)
  55. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Yi-Pey Luo, Yi-Ling Chen*. Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer. Oncology Reports 2015 Jan; 33(1): 49-57. (SCI, co-first authors)
  56. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen*. Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model. Oncology Reports 2014 Dec; 32(6): 2335-2342. (SCI, co-first authors)
  57. Ying-Jui Chao, Edgar D Sy, Hui-Ping Hsu, Yan-Shen Shan*. Predictors for resectability and survival in locally advanced pancreatic cancer after gemcitabine based neoadjuvant therapy. BMC Surgery 2014 Sep 25; 14(9): 72.e1-72.e8. (SCI)
  58. Yu-Hsuan Hung, Yi-Shin Chan, Yung-Sheng Chang, Kuo-Ting Lee, Hui-Ping Hsu, Meng-Chi Yen, Wei-Ching Chen, Chih-Yang Wang, Ming-Derg Lai*. Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma. Oncology Reports 2014 Jun; 31(6): 2797-2803. (SCI)
  59. Hau-Lun Huang, Hui-Ping Hsu, Shu-Chu Shieh, Yung-Sheng Chang, Wei-Ching Chen, Chien-You Cho, Chiao-Fang Teng, Ih-Jen Su, Wen-Chun Hung, Ming-Derg Lai*. Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide. Mol Cancer Ther. 2013 Nov; 12(11): 2505-2516. (SCI)
  60. Yao-Lung Kuo, Wen-Chung Chen, Wei-Jen Yao, Lili Cheng, Hui-Ping Hsu, Hung-Wen Lai, Shou-Jen Kuo, Dar-Ren Chen*, Tsai-Wang Chang*. Validation of Memorial Sloan-Kettering Cancer Center nomogram for prediction of non-sentinel lymph node metastasis in sentinel lymph node positive breast cancer patients an international comparison. Int J Surg 2013 Aug; 11(7): 538-543. (SCI)
  61. Yan-Shen Shan, Jung-Hua Fang, Ming-Derg Lai, Meng-Chi Yen, Pin-Wen Lin, Hui-Ping Hsu, Chian-Yuh Lin, Yi-Ling Chen*. Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules. Mol Carcinog 2011 Oct; 50(10): 739-750. (SCI)
  62. I-Wen Lee, Lin Kang, Hui-Ping Hsu, Pao-Lin Kyo, Chia-Ming Chang*. Puerperal mastitis requiring hospitalization during a nine-year period. Am J Obstet Gynecol 2010 Oct; 203(4): 332.e1-e6. (SCIE)
  63. Te-Ling Lu, Guan-Jhong Huang, Huang-Joe Wang, Jian-Lian Chen, Hui-Ping Hsu, Te-Jung Lu*. Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy. Biochem Biophys Res Commun 2010 Jul; 398(1): 26-31. (SCI)
  64. Hui-Ping Hsu, Yan-Shen Shan, Ming-Derg Lai, Pin-Wen Lin*. Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival. Cancer Biol Ther 2010 Jul 15; 10(2): 144-154. (SCI, first author)
  65. Hui-Ping Hsu, Yan-Shen Shan, Pin-Wen Lin*, Ying-Tai Jin, Ming-Derg Lai. Loss of E-cadherin and b-catenin is correlated with poor prognosis of ampullary neoplasms. J Surg Oncol 2010 Apr 1; 101(5): 356-362. (SCI, first author)
  66. Hui-Ping Hsu. Prognosis of ampullary carcinoma after radical resection and its carcinogenesis. Formos J Surg 2008 Dec; 41(6): 257-261. (Mini Review)
  67. Hui-Ping Hsu, Yan-Shen Shan*, Yu-Hsiang Hsieh, Ta-Ming Yang, Pin-Wen Lin. Predictors of recurrence after pancreaticoduodenectomy in ampullary cancer: comparison between non-, early and late recurrence. J Formos Med Assoc 2007 Jun; 106(6): 432-443. (SCI, first author)
  68. Paul J. Karanicolas*, Edward Davies, Regina Kunz, Matthias Briel, H. Pavan Koka, Darrin M. Payne, Shona E. Smith, Hui-Ping Hsu, Pin-Wen Lin, Christian Bloechle, Karl-Joseph Paquet and Gordon H. Guyatt. The pylorus: take it or leave it? Systemic review and meta-analysis of pylorus-preserving versus standard Whipple pancreaticoduodenectomy for pancreatic or periampullary cancer. Ann Surg Oncol 2007 Jun; 14(6): 1825-1834. (SCI)
  69. Hui-Ping Hsu, Ta-Ming Yang, Yu-Hsiang Hsieh, Yan-Shen Shan*, Pin-Wen Lin. Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. Ann Surg Oncol 2007 Jan; 14(1): 50-60. (SCI, first author)
  70. Hui-Ping Hsu, Yan-Shen Shan*, Yu-Hsiang Hsieh, Edgar D. Sy, Pin-Wen Lin. Impact of Etiologic factors and APACHE II and POSSUM scores in management and clinical outcome of acute intestinal ischemic disorders after surgical treatment. World J Surg 2006 Dec; 30(12): 2152-2162. (SCI, first author)
  71. Hui-Ping Hsu, Yan-Shen Shan, Edgar D. Sy, Pin-Wen Lin*. Acute mesentery venous occlusion in patients with warfarin – warfarin therapy may complicate the diagnosis of intestinal vascular complication. Formosan J Surgery 2005 Feb; 38(1): 13-19. (First author)
  72. Yan-Shen Shan, Hui-Ping Hsu, Yu-Hsiang Hsieh, Edgar D. Sy, Jenq-Chang Lee, Pin-Wen Lin*. The significance of intraoperative peritoneal fungus culture in perforated peptic ulcer. Br J Surg 2003 Oct; 90: 1215-9. (SCI)
  73. Hui-Ping Hsu, Pao-Lin Kuo*, Meng-Hsing Wu, Ta-Jen Wu, Yuan-Chang Dai, Ching-Cherng Tzeng, Shio-Jean Lin. Microscopic gonadoblastoma in a patient with 46,XY gonadal dysgenesis. Taiwanese J Obstet Gynecol 2001; 40: 77-81. (SCI, first author)
  74. Nina Tsao, Hui-Ping Hsu, Ching-Ming Wu, Ching-Chuan Liu, Huan-Yao Lei*. TNF causes an increase in blood-brain barrier permeability during sepsis. J Med Microbiol 2001 Sep; 50(9): 812-821. (SCI)
  75. Nina Tsao, Hui-Ping Hsu, Huan-Yao Lei*. TNFalpha-induced cyclooxygenase-2 not only increases the vasopermeability of blood-brain barrier but also enhances the neutrophil survival in Escherichia coli-induced brain inflammation. Prostaglandins & Other Lipid Mediators. 1999 Jul; 57(5-6): 371-382. (SCI)
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